A successful collaboration between several European and Japanese labs led to a publication in the prestigious American journal Science on the role of plant-specific sphingolipids on the toxicity of microbial toxins.
Adiilah Mamode-Cassim and Sébastien Mongrand get involved in the lipid part, and the purification of this so peculiar plant-specific lipids!
Eudicot plant-specific sphingolipids determine host selectivity of microbial NLP cytolysins. Lenarčič T, Albert I, Böhm H, Hodnik V, Pirc K, Zavec AB, Podobnik M, Pahovnik D, Žagar E, Pruitt R, Greimel P, Yamaji-Hasegawa A, Kobayashi T, Zienkiewicz A, Gömann J, Mortimer JC, Fang L, Mamode-Cassim A, Deleu M, Lins L, Oecking C, Feussner I, Mongrand S, Anderluh G, Nürnberger T. Science. 2017 Dec 15;358(6369):1431-1434. doi: 10.1126/science.aan6874.
A comment in the same issue of Science is also available:
How plants differ in toxin-sensitivity. Van den Ackerveken G. Science. 2017 Dec 15;358(6369):1383-1384. doi: 10.1126/science.aar4188.
